Patents

Ref. No. Title Description of Subject Matter/Claims  
58486-701.101

 

 

 ROCK2 INHIBITORS AND USE THEREOF

 

 A method of treating a viral infection in a human subject in need thereof, comprising administering to the human subject a therapeutically effective amount of a rho associated kinase 2 (ROCK2) antagonist.

A method of treating a viral infection in a human subject in need thereof, comprising administering to the human subject a therapeutically effective amount of a composition comprising:

(a) a rho associated kinase 2 (ROCK2) antagonist; and

(b) a pharmaceutically acceptable carrier or excipient.

A method of treating a viral infection in a human subject in need thereof, comprising administering to the human subject a therapeutically effective amount of a composition comprising:

(a) a rho associated kinase 2 (ROCK2) antagonist; and

(b) at least one other antiviral agent.

  
58486-701.102

 

 

 ROCK2 INHIBITORS AND USE THEREOF

 

 A method of treating a viral infection in a human subject in need thereof, comprising administering to the human subject a therapeutically effective amount of a rho associated kinase 2 (ROCK2) antagonist.

 A method of treating a viral infection in a human subject in need thereof, comprising administering to the human subject a therapeutically effective amount of a composition comprising:

(a) a rho associated kinase 2 (ROCK2) antagonist; and

(b) a pharmaceutically acceptable carrier or excipient.

A method of treating a viral infection in a human subject in need thereof, comprising administering to the human subject a therapeutically effective amount of a composition comprising:

(a) a rho associated kinase 2 (ROCK2) antagonist; and

(b) at least one other antiviral agent.
58486-701.103

 

 

 ROCK2 INHIBITORS AND USE THEREOF

 

 A method of treating a viral infection in a human subject in need thereof, comprising administering to the human subject a therapeutically effective amount of a rho associated kinase 2 (ROCK2) antagonist, wherein the human subject has fibrosis, scarring on lungs, or Kawasaki disease.

A method of treating a viral infection in a human subject in need thereof, comprising administering to the human subject a therapeutically effective amount of a composition comprising:

(a) a rho associated kinase 2 (ROCK2) antagonist; and

(b) a pharmaceutically acceptable carrier or excipient;

wherein the human subject has fibrosis, scarring on lungs,  or Kawasaki disease.

A method of treating a viral infection in a human subject in need thereof, comprising administering to the human subject a therapeutically effective amount of a composition comprising:

(a) a rho associated kinase 2 (ROCK2) antagonist; and

(b) at least one other antiviral agent;

wherein the human subject has fibrosis, scarring on lungs, or Kawasaki disease.

 

  
58486-702.101

 

 LIQUID FORMULATION OF AVERMECTIN

 
  1. A composition comprising a therapeutically effective amount of a compound of Formula I,

 

  
58486-703.101

 

 TREATMENT OF NEUROLOGICAL DISORDERS 

USING LIQUID FORMULATIONS OF AVERMECTINS

 

 A method for treating a neurological disorder, comprising:

administering a formulation to a human subject in need of such treatment, the formulation comprising

            (a) a therapeutically effective amount of a composition; and

            (b) at least one stabilizing agent comprising a liquid excipient;

wherein the composition comprises at least one compound of Formula I:

 

  
58486-704.101

 

 TREATMENT OF VIRAL INFECTION

USING LIQUID FORMULATIONS OF  AVERMECTINS

 

 A method for treating a viral infection, comprising:

administering a formulation to a human subject in need of such treatment, the formulation comprising

            (a) a therapeutically effective amount of a composition; and

            (b) at least one stabilizing agent comprising a liquid excipient;

wherein the composition comprises at least one compound of Formula I:

 

 

 

  
58486-705.101

 

 TREATMENT OF PAIN USING LIQUID FORMULATIONS OF AVERMECTINS

 

 A method for treating pain in a human subject, comprising:

administering a formulation to the human subject in need of such treatment, the formulation comprising:

            a therapeutically effective amount of a composition; 

wherein the composition comprises at least one compound of Formula I . . .

 

  
58486-706.101

 

 TREATMENT OF SPINAL SPASTICITY USING LIQUID FORMULATIONS OF AVERMECTINS

 

 A method for treating spasticity in a human subject, comprising:

administering a formulation to the human subject in need of such treatment, the formulation comprising:

            a therapeutically effective amount of a composition; 

wherein the composition comprises at least one compound of Formula I . . .